Direct Aniline Formation with Benzene and Hydroxylamine

نویسندگان

چکیده

A single-step method for aniline formation was examined. Using a vanadate catalyst with an iron oxide co-catalyst and hydroxylamine hydrochloride as the amine source, up to 90% yield of obtained high selectivity. Further study showed that overall reaction pseudo-second order in terms concentration. Regioselective H-D exchange experiments suggest C-N bond step occurs via irreversible electrophilic pathway. Based on all key observations, mechanism is proposed.

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ژورنال

عنوان ژورنال: Chemistry

سال: 2023

ISSN: ['2624-8549']

DOI: https://doi.org/10.3390/chemistry5040139